Suggested fix (unconfirmed): Turn off ray tracing before entering Panghzen. If the crash persists, clear your display driver cache and force a full shader
No confirmed fix yet. Players suggest: You can try deleting the "projectpbz/saved/cache" folder in the game directory, and then recompile the shaders in the game.
Suggested fix (unconfirmed): Parry her red attacks to deal heavy damage to her guard, and use your dodge for everything else. Keep your distance to trigger her predictable charges, and switch weapons if your guard is about to break.
Suggested fix (unconfirmed): Compress your save file into a .zip or .rar format, or rename the file extension to .txt. Then, submit a bug report with the file attached through the official customer support portal.